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张莹
发布时间:2020-12-30 发布者:泮红飞? 浏览次数:1300?

  张莹,教授,博士生导师,山东省泰山学者青年专家。主持国家自然科学基金项目3项,作为合作单位负责人参与国家自然科学基金1项,主持山东省自然科学基金1项,主持山东省高校青创科技支持计划1项,总经费200余万元。以第一作者或通讯作者发表学术论文30余篇,引用500余次,其中1篇论文入选ESI1%)高被引论文。获海洋科学技术奖二等奖1项,山东省高等开云app官网入口科学技术奖二等奖1项、三等奖1 项。授权发明专利3项,申请发明专利1项。荣获烟台市创新驱动先进个人、滨州市青年科技奖等称号。长期从事科普工作,受聘为烟台市科普专家。

 

代表性科研项目:

1. 国家自然科学基金(82172560):幽门螺杆菌激活YAP调控Wnt信号影响自噬在胃癌发生发展中的作用机制. 2022-2025,经费55万元。项目负责人。

2. 2021年度泰山学者青年专家项目,经费75万元。

3. 国家自然科学基金(81771709: 整合素调控的自噬/凋亡在幽门螺杆菌感染免疫逃逸中的作用机制研究.2018-2021,经费60万元。项目负责人。

4. 山东省高等开云app官网入口青创科技支持计划(2019KJK012):整合素连接激酶调控的自噬在幽门螺杆菌感染免疫逃逸中的作用机制研究。2019-2021,经费25万元。创新团队负责人。

发表学术论文(第一或通讯作者):

1. Boqing Li, Xin Lv, Zheng Xu, Jing He, SiSi Liu, Xiaolin Zhang, Xiaohan Tong, Jing Li, Ying Zhang*. Helicobacter pylori infection induces autophagy via ILK regulation of NOXs?ROS?Nrf2/HO?1?ROS loop. World Journal of Microbiology and Biotechnology (2023) 39:284.

2. Xiaohan Tong, Boqing Li, Jing Li, Lan Li, Ruiqing Zhang, Yunqiu Du, Ying Zhang*. Polyethylene microplastics cooperate with Helicobacter pylori to promote gastric injury and inflammation in mice. Chemosphere 288(2022)132579.

3. Boqing Li, Qianyu Rong, Yunqiu Du, Ruiqing Zhang, Jing Li, Xiaohan Tong, · Li Geng1, Ying Zhang*. Regulation of β1?integrin in autophagy and apoptosis of gastric epithelial cells infected with Helicobacter pylori. World Journal of Microbiology and Biotechnology (2022) 38:12.

4. Zheng Xu, Boqing Li, Yunqiu Du, Ruiqing Zhang, Xiaohan Tong, Jing Li, Yulong Wu, Xiaofei Ji, Ying Zhang*. Helicobacter pylori regulates ILK to influence autophagy through Rac1 and RhoA signaling pathways in gastric epithelial cells. Microbial Pathogenesis158(2021)105054.

5. Yunfei Ding, Ruiqing Zhang, Boqing Li, Yunqiu Du, Jing Li, Xiaohan Tong, Yulong Wu, Xiaofei Ji, Ying Zhang*. Tissue distribution of polystyrene nanoplastics in mice and their entry, transport, and cytotoxicity to GES-1 cells. Environmental Pollution 280 (2021) 116974.

6. Boqing Li, Yunfei Ding, Xue Cheng, Dandan Sheng, Zheng Xu, Qianyu Rong,Yulong Wu, Huilin Zhao, Xiaofei Ji, Ying Zhang*. Polyethylene microplastics affect the distribution of gut microbiota and inflammation development in mice. Chemosphere 244 (2020) 125492.

7. Ying Zhang, Jiaojiao Li, Qianyu Rong, Zheng Xu, Yunfei Ding, Qizhi Cao, Xiaofei Ji, Huilin Zhao, Yulong Wu, Boqing Li. The regulatory role of C1q on Helicobacter pylori-induced inflammatory cytokines secretion in THP-1 cells. Microbial Pathogenesis 131 (2019) 234–238.

8. Huijing Zhang, Xuemei Yao, Yunfei Ding, Zheng Xu, Rongning Liang, Ying Zhang?, Yulong Wu, Boqing Li, Bo Guan. PI3K signaling pathways modulated white spot syndrome virus (WSSV) replication in Procambarus clarkia. Fish and Shellfish Immunology 76 (2018) 279–286.

9. Ying Zhang, Hui Sun, Jiaojiao Li, Qianyu Rong, Xiaofei Ji, Boqing Li. The leukocyte-associated immunoglobulin (Ig)elike receptor-1 modulating cell apoptosis and inflammatory cytokines secretion in THP-1 cells after Helicobacter pylori infection. Microbial Pathogenesis 109 (2017) 292–299.

10. Ying Zhang, Hui Sun, Huilin Zhao, Xingxing Chen, Jiaojiao Li, Boqing Li. The leukocyte-associated immunoglobulin (Ig)elike receptor-1 modulating cell apoptosis and inflammatory cytokines secretion in THP-1 cells after Helicobacter pylori infection. Microbial Pathogenesis 109 (2017) 292–299.

11. Ying Zhang, Huifeng Wu, LeiWei, Zeping Xie, Bo Guan. Effects of hypoxia in the gills of theManila clamRuditapes philippinarum using NMR-based metabolomics. Marine Pollution Bulletin 114 (2017) 84–89.

12. Ying Zhang, Hui Sun, Xingxing Chen, Jiaojiao Li, Huilin Zhao, Li Geng, Boqing Li. Functional profile of gastric epithelial cells infected with Helicobacter pylori strains. Microbial Pathogenesis 95 (2016) 77–81.

 


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